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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRF7 All Species: 16.67
Human Site: S477 Identified Species: 40.74
UniProt: Q92985 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92985 NP_001563.2 503 54278 S477 V S S L D S S S L S L C L S S
Chimpanzee Pan troglodytes XP_001147267 439 48559 S413 V S S L D S S S L S L C L S S
Rhesus Macaque Macaca mulatta XP_001092569 500 56291 S442 E L S W S A D S I R L Q I S N
Dog Lupus familis XP_540526 284 31613 S265 S L G L C L S S S N S L Y E D
Cat Felis silvestris
Mouse Mus musculus P70434 457 51203 S431 V S S L D S S S L G L C L S S
Rat Rattus norvegicus NP_001028863 455 50697 S429 V S S L D S S S L G L C L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508806 462 52633 E442 F R L L Q T Q E S W P P M H P
Chicken Gallus gallus Q90643 491 54423 N468 A S S L N S G N V S L Q L S D
Frog Xenopus laevis NP_001079588 466 52659 E437 A S S L H S S E I N L E I S D
Zebra Danio Brachydanio rerio NP_956971 423 49042 Q404 R N D N V S L Q I S H N S L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.7 28.2 43.7 N.A. 62.6 63.8 N.A. 28 41.5 25.8 31.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 82.5 41.9 48.5 N.A. 69.5 70.9 N.A. 43.1 53.2 43.3 46.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 20 N.A. 93.3 93.3 N.A. 6.6 53.3 46.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 53.3 26.6 N.A. 93.3 93.3 N.A. 20 73.3 66.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 40 0 0 0 % C
% Asp: 0 0 10 0 40 0 10 0 0 0 0 0 0 0 30 % D
% Glu: 10 0 0 0 0 0 0 20 0 0 0 10 0 10 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 0 0 20 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 10 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 30 0 0 0 20 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 20 10 80 0 10 10 0 40 0 70 10 50 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 10 0 10 10 0 0 10 0 20 0 10 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 10 % P
% Gln: 0 0 0 0 10 0 10 10 0 0 0 20 0 0 0 % Q
% Arg: 10 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 10 60 70 0 10 70 60 60 20 40 10 0 10 70 40 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 40 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _